Which of the following are associated with diabetes mellitus, a common disease in adults? 1. Higher sugar level in blood 2. Lower sugar level in blood 3. Lower insulin level in blood 4. Higher insulin level in blood Select the correct answer by using the codes given below: Codes:

1. Diabetes mellitus is a metabolic disorder characterized by high blood sugar levels over a prolonged period. 2. This high blood sugar (hyperglycemia) occurs either because the pancreas does not produce enough insulin, or the cells of the body do not respond properly to the insulin produced. 3. Therefore, a common feature is a higher sugar level in blood (Statement 1 is correct). 4. Correspondingly, there is often a relative or absolute deficiency of insulin, meaning a lower insulin level in blood (or ineffective insulin action) (Statement 3 is correct). 5. Statements 2 (Lower sugar level) and 4 (Higher insulin level) are generally contrary to the condition of diabetes mellitus (though high insulin can occur in early Type 2 diabetes/insulin resistance, the defining feature is high blood sugar). 6. Thus, statements I and III are associated with diabetes mellitus.