Consider the following statements: 1. Non-function of lachrymal gland is an important symptom of deficiency of Vitamin A. 2. Deficiency of Vitamin B1 can lead to indigestion and heart enlargement. 3. Vitamin C deficiency can lead to pain in the muscles. 4. Deficiency of Vitamin D causes increased loss of Ca++ in urine. Which of the statements given above are correct?

1 Statement 1 is correct. Deficiency of Vitamin A leads to xerophthalmia, a condition affecting the eyes, including the non-function or drying of the lachrymal glands, causing dry eyes. 2 Statement 2 is correct. Deficiency of Vitamin B1 (Thiamine) causes Beriberi, which can manifest with neurological and cardiovascular symptoms, including indigestion and heart enlargement (cardiac beriberi). 3 Statement 3 is incorrect. While general weakness and fatigue can occur, the primary symptom of severe Vitamin C deficiency (Scurvy) is related to collagen synthesis breakdown (e.g., bleeding gums, poor wound healing), not specifically pain in the muscles as a defining feature. 4 Statement 4 is incorrect. Deficiency of Vitamin D impairs calcium absorption from the gut, leading to bone problems (rickets, osteomalacia). It does not typically cause an increased loss of Ca++ in urine; in fact, parathyroid hormone levels might rise to conserve calcium.