GS PrelimsScience and TechnologyHuman Health and Diseases2003

With reference to normal human beings consider the following statements: 1. 1. In response to the presence of HCL, secretian is produced from the duodenum 2. 2. Enterogastrone is produced in the small intestine in response to the presence of fatty acids Which of these statements is/are correct?

A

Only 1

B

Only 2

C

Both 1 and 2

D

Neither 1 nor 2

Correct Answer: Option C

Explanation

1. The question asks to verify two statements regarding digestion in normal human beings. 2. Statement 1: In response to the presence of HCL (hydrochloric acid from the stomach entering the duodenum), secretin is produced from the duodenum. This is correct. Acidic chyme entering the duodenum stimulates S cells in the duodenal lining to release the hormone secretin. Secretin, in turn, stimulates the pancreas to release bicarbonate-rich fluid to neutralize the acid. 3. Statement 2: Enterogastrone is produced in the small intestine in response to the presence of fatty acids. This is correct. Enterogastrone (now understood to be a group of hormones like CCK and secretin, or specifically referring to GIP - gastric inhibitory peptide) is released from the small intestine (duodenum/jejunum) when fats or acids are present. These hormones inhibit gastric motility and secretion, slowing down stomach emptying. 4. Since both statements 1 and 2 are physiologically correct, the correct option is (C).

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