Four-digit numbers are to be formed using the digits 1, 2, 3 and 4; and none of these four digits are repeated in any manner. Further,
1. 2 and 3 are not to immediately follow each other
2. 1 is not to be immediately followed by 3
3. 4 is not to appear at the last place
4. 1 is not to appear at the first place
How many different numbers can be formed ?